PT302 WBS
2025-06-13 17:13:11 2 Report
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PT302
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Outline/Content
A.3. Cell fusion and screening
D.3. Non-GLP toxicology in healthy target animal
E.1. Developing canine MG sample analysis method
C.1. Obtain candidate protein
D.1. Preclinical CMC
A.7. Acceptance check
A. Antibody Lead Discovery選(2025/01 to 2025/09)
C.2. Potency assay of cananized candidate
A.6. Antibody production and binding affinity validation
D. PK/PD & non-GLP Toxicology Evaluation(2026/01 to 2026/12)
E. Method development(2026/10 to 2026/12)
B. Optimization of Candidate(2025/09 to 2025/12)
A.1 Material preparation
C. Small-Scale Candidate Production and Potency Assay(2025/12 to 2026/01)
B.1. Cananization and affinity maturation
A.5. Sequencing
A.4. Subclonal selection
D.2. PK/PD in healthy target animal
A.2. Mice immunization

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